Miranda McManus

Miranda McManus

Adjunct Instructor


M.S. - University of Charleston
B.S. (2), B.A.  - College of Charleston

Research Interests

My background is in molecular genetics, and my primary research interest is improving outcomes in the autosomal dominant tumor-predisposing genetic conditions neurofibromatosis and schwannomatosis (NF/SWN). I am actively involved in the Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International Collaboration, which works to achieve consensus within the NF/SWN community regarding future clinical trials and to accelerate the identification of agents which will benefit individuals with NF/SWN.

Courses Taught 

BIOL 101: Concepts and Application in Biology I
BIOL 102: Concepts and Application in Biology II
BIOL 111: Introduction to Cell and Molecular Biology
BIOL 112: Evolution, Form, and Function of Organisms
BIOL 305: Genetics

Selected Publications 

Staedke V, Anstett KA, Bedwell DM, Giovannini M, Keeling KM, Kesterson RA, Kim, YM, Korf BR, Leier A, McManus ML, Sarnoff HL, Vitte J, Walker JA, Plotkin SR, Wallis D. Gene-targeted therapy for neurofibromatosis and schwannomatosis: the path to clinical trials. Clinical Trials. 2023.

Gross AM, Plotkin SR, Watts NB, Fisher MJ, Klesse LJ, Lessing AJ, McManus ML, Larson AN, Oberlander B, Rios JJ, Sarnoff H, Simpson BN, Ullrich NJ, Stevenson DA. Potential endpoints for assessment of bone health in persons with neurofibromatosis type 1. Clinical Trials. 2023. doi: 10.1177/17407745231201338. PMID: 37772407.

Merker VL, Thompson HL, Wolters PL, Buono FD, Hingtgen CM, Rosser T, Barton B, Barnett C, Smith T, Haberkamp D, McManus ML, Baldwin A, Moss IP, Röhl C, and Martin S. Recommendations for Assessing Appearance Concerns Related to Plexiform and Cutaneous Neurofibromas in Neurofibromatosis 1 Clinical Trials. Clinical Trials. 2023.

Honors & Awards

Distinguished Adjunct Faculty Teaching Award, 2015
Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International
Collaboration Outstanding Service Award, 2023